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This is, in part, because price increases reduce initiation of tobacco use among young people and could make smoking more prohibitive for low-income smokers

According to the Center for Disease Control, approximately 16 million Americans have at least one disease associated with cigarette smoking

Future investigations should integrate longitudinal human cohorts with mechanistic animal studies colonized by smoker-derived microbiota, which may provide causal insight into how specific taxa or metabolites mediate disease trajectories

Milara J, Peir T, Serrano A, Cortijo J

At this late date here in the Legislature, it would be very difficult, Palace said

PMID 2136102